OBSERVATIONAL STUDY

This observational study will observe the hormetic effects of a microdose, in real-world, real-time, wellness activities.

Informed Consent

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Find your optimal dose… in a MICRODOSE

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Observational Studies

Registered patients, wellness, & legacy users will find their optimal dose, via microdose.

Participants will titrate their optimal dose (sweet spot) via microdose. The metered dose allows clinicians and patients to more accurately monitor individual usage by dosage.

Mental Health

Evaluate microdosing schedules for treatments of psychiatric symptoms.

PubMED: Cannabinoids and their therapeutic applications in mental disorders – “It is important to emphasize that cannabis consumption affects anxiety-related behaviors in a dose-dependent manner, with ‘low doses’ being anxiolytic and high doses inducing increased anxiety and panic.”

BRAZIER™ delivers thrice filtered microdoses of cannabis flower, which helps to reduce anxiety.

Physical Health

Medical cannabis inhalation usurps opioids by 95% in 5 year study on treating chronic pain.

Study: Cannabis Inhalation Associated With Long-Term Pain Relief, Opioid-Sparing Effects in Patients With Treatment-Resistant Lower Back Pain “These findings contribute evidence toward potential clinical benefits of medical cannabis in reducing prescription opioid intake, which may decrease patients’ risk of opioid overdose.“

Study Goals

Establish a standardized microdose of cannabis for inhalation in a MDI-P.

This observational study of “randomized compartive-effectiveness trials of dry herb inhalation” is on the (Hormetic Effects of a Microdose of Botanical Cannabis on Mental Health Interventions, and Pain Management, Including Opioid Replacement Therapy on Adults, Seniors, Veterans & Athletes), seeks to establish a standardized microdose of botanical cannabis for use in a Metered Dose Inhaler-Pipette (MDI-P), with considerations for use in other Pulmonary Inhalers, i.e. Metered Dose Inhaler (MDI), Dry Powder Inhaler (DPI), or Dry Herb Vaporizer.

The observational study will follow up the mechanistic studies of recorded dosing schedules on THC/CBD ratios, optimal dose (sweet-spot), and route to pain phenotypes. The ancillary study will contribute to a greater body of botanical cannabis research by using metered dose inhalation that addresses limitations on a standardized inhalation method and a standardized dose, and more importantly, a microdose to mitigate cannabis use disorder. Observations of Wellness activities will be conducted in real-time, and real-world settings.